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1

The role of protease-activated receptors PAR-1 and PAR-2 in the repair of 16HBE 14o− epithelial cell monolayers in vitro

D. Ewen, S.L. Clarke, J.R. Smith, C. Berger, G. Salmon, M. Trevethick, J.K. Shute

Journal:

Clinical & Experimental Allergy

Year:

2010

Language:

english

File:

PDF, 440 KB

english, 2010

2

THE β3-ADRENOCEPTOR AGONIST CL316243 PREVENTS INDOMETHACIN-INDUCED JEJUNAL ULCERATION IN THE RAT BY REVERSING EARLY VILLOUS SHORTENING

ANTHONY, ANDREW, BAHL, ASHWANI K., OAKLEY, IAN G., SPRAGGS, COLIN F., DHILLON, AMAR P., TREVETHICK, MICHAEL A., PIASECKI, CHRISTOPHER, POUNDER, ROY E., WAKEFIELD, ANDREW J.

Journal:

The Journal of Pathology

Year:

1996

Language:

english

File:

PDF, 911 KB

english, 1996

3

Deregulation ofCLN1 andCLN2 in theSaccharomyces cerevisiae whi2 Mutant

RADCLIFFE, PIPPA, TREVETHICK, JANET, TYERS, MIKE, SUDBERY, PETER

Journal:

Year:

1997

Language:

english

File:

PDF, 144 KB

english, 1997

4

The yeastPRS3 gene is required for cell integrity, cell cycle arrest upon nutrient deprivation, ion homeostasis and the proper organization of the actin cytoskeleton

Binley, K. M., Radcliffe, P. A., Trevethick, J., Duffy, K. A., Sudbery, P. E.

Journal:

Year:

1999

Language:

english

File:

PDF, 359 KB

english, 1999

5

Effects of isolation and culture on prostaglandin synthesis by porcine aortic endothelial and smooth muscle cells

Ann Ager, John L. Gordon, Salvador Moncada, Jeremy D. Pearson, John A. Salmon, Michael A. Trevethick

Journal:

Journal of Cellular Physiology

Year:

1982

Language:

english

File:

PDF, 964 KB

english, 1982

6

Highly potent and selective zwitterionic agonists of the δ-opioid receptor. Part 1

Donald S. Middleton, Graham N. Maw, Clare Challenger, Alan Jessiman, Patrick S. Johnson, William A. Million, Carly L. Nichols, Jenny A. Price, Michael Trevethick

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2006

Language:

english

File:

PDF, 146 KB

english, 2006

7

The discovery of long acting β2-adrenoreceptor agonists

Alan D. Brown, Mark E. Bunnage, Paul A. Glossop, Kim James, Rhys Jones, Charlotte A.L. Lane, Russell A. Lewthwaite, Simon Mantell, Christelle Perros-Huguet, David A. Price, Mike Trevethick, Rob Webste

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2007

Language:

english

File:

PDF, 135 KB

english, 2007

8

Design and synthesis of a fluorescent muscarinic antagonist

Lyn H. Jones, Amy Randall, Carolyn Napier, Mike Trevethick, Sasha Sreckovic, Jessica Watson

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2008

Language:

english

File:

PDF, 102 KB

english, 2008

9

The discovery of adamantyl-derived, inhaled, long acting β2-adrenoreceptor agonists

Alan D. Brown, Mark E. Bunnage, Paul A. Glossop, Kim James, Rhys Jones, Charlotte A.L. Lane, Russell A. Lewthwaite, Simon Mantell, Christelle Perros-Huguet, David A. Price, Mike Trevethick, Rob Webste

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2008

Language:

english

File:

PDF, 118 KB

english, 2008

10

Inhaled adenosine A2A receptor agonists for the treatment of chronic obstructive pulmonary disease

Simon J. Mantell, Peter T. Stephenson, Sandra M. Monaghan, Graham N. Maw, Michael A. Trevethick, Michael Yeadon, Ruth F. Keir, Don K. Walker, Rhys M. Jones, Matthew D. Selby, David V. Batchelor, Stuar

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2008

Language:

english

File:

PDF, 138 KB

english, 2008

11

SAR of a series of inhaled A2A agonists and comparison of inhaled pharmacokinetics in a preclinical model with clinical pharmacokinetic data

Simon J. Mantell, Peter T. Stephenson, Sandra M. Monaghan, Graham N. Maw, Michael A. Trevethick, Michael Yeadon, Don K. Walker, Matthew D. Selby, David V. Batchelor, Stuart Rozze, Helene Chavaroche, A

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2009

Language:

english

File:

PDF, 895 KB

english, 2009

12

Effect of methylprednisolone on the ulceration, matrix metalloproteinase distribution and eicosanoid production in a model of colitis in the rabbit

DANIEL ANTHONY, FELICITY SAVAGE, PAUL BOULOS, ROSALIND HEMBRY, VIRGINIA SAMS, MICHAEL TREVETHICK

Journal:

International Journal of Experimental Pathology

Year:

1997

Language:

english

File:

PDF, 446 KB

english, 1997

13

The MET3 promoter: a new tool for Candida albicans molecular genetics

R. S. Care, J. Trevethick, K. M. Binley, P. E. Sudbery

Journal:

Molecular Microbiology

Year:

1999

Language:

english

File:

PDF, 295 KB

english, 1999

14

Inhibition of constitutive and inducible cyclooxygenase activity in human platelets and mononuclear cells by NSAIDS and Cox 2 inhibitors

C. J. Grossman, J. Wiseman, F. S. Lucas, M. A. Trevethick, P. J. Birch

Journal:

Inflammation Research

Year:

1995

Language:

english

File:

PDF, 489 KB

english, 1995

15

Leukotrienes do not contribute to the pathogenesis of indomethacin-induced ulceration of the gastric antrum in the re-fed rat

M. A. Trevethick, N. M. Clayton, A. K. Bahl, P. Strong, I. W. Harman

Journal:

Inflammation Research

Year:

1994

Language:

english

File:

PDF, 480 KB

english, 1994

16

Neutrophil infiltration does not contribute to the ulcerogenic effects of indomethacin in the rat gastric antrum

M. A. Trevethick, A. K. Bahl, N. M. Clayton, P. Strong, S. Sanjar, I. W. Harman

Journal:

Inflammation Research

Year:

1994

Language:

english

File:

PDF, 773 KB

english, 1994

17

The role of acid in the pathogenesis of indomethacin-induced gastric antral ulcers in the rat.

NM Clayton, I Oakley, LV Williams, MA Trevethick

Journal:

Alimentary Pharmacology & Therapeutics

Year:

1996

Language:

english

File:

PDF, 242 KB

english, 1996

18

Early histological features of small intestinal injury induced by indomethacin

A. ANTHONY, A. P. DHILLON, G. NYGARD, M. HUDSON, C. PIASECKI, P. STRONG, M. A. TREVETHICK, N. M. CLAYTON, C. C. JORDAN, R. E. POUNDER, A. J. WAKEFIELD

Journal:

Alimentary Pharmacology & Therapeutics

Year:

1993

Language:

english

File:

PDF, 1.57 MB

english, 1993

19

Gastric anti-secretory, mucosal protective, anti-pepsin and anti-Helicobacter properties of ranitidine bismuth citrate

R. STABLES, C. J. CAMPBELL, N. M. CLAYTON, J. W. CLITHEROW, C. J. GRINHAM, A. A. McCOLM, A. McLAREN, M. A. TREVETHICK

Journal:

Alimentary Pharmacology & Therapeutics

Year:

1993

Language:

english

File:

PDF, 839 KB

english, 1993

20

Fibrin formation by wounded bronchial epithelial cell layers in vitro is essential for normal epithelial repair and independent of plasma proteins

M. J. Perrio, D. Ewen, M. A. Trevethick, G. P. Salmon, J. K. Shute

Journal:

Clinical & Experimental Allergy

Year:

2007

Language:

english

File:

PDF, 700 KB

english, 2007

21

Is uridine a treatment for asthma?

M. A. Trevethick

Journal:

Clinical & Experimental Allergy

Year:

2010

Language:

english

File:

PDF, 66 KB

english, 2010

22

Ligand binding assays at equilibrium: validation and interpretation

Edward C. Hulme, Mike A. Trevethick

Journal:

British Journal of Pharmacology

Year:

2010

Language:

english

File:

PDF, 1.14 MB

english, 2010

23

Treating lung inflammation with agonists of the adenosine A2A receptor: promises, problems and potential solutions

M A Trevethick, S J Mantell, E F Stuart, A Barnard, K N Wright, M Yeadon

Journal:

British Journal of Pharmacology

Year:

2008

Language:

english

File:

PDF, 204 KB

english, 2008

24

Suppression of inflammatory and immune responses by the A2A adenosine receptor: an introduction

T M Palmer, M A Trevethick

Journal:

British Journal of Pharmacology

Year:

2008

Language:

english

File:

PDF, 156 KB

english, 2008

25

Neutrophil depletion does not prevent indomethacin-induced ulceration of the rat gastric antrum

M. A. Trevethick, N. M. Clayton, A. K. Bahl, S. Sanjar, P. Strong

Journal:

Inflammation Research

Year:

1994

Language:

english

File:

PDF, 165 KB

english, 1994

26

Non-steroidal anti-inflammatory drug-induced gastric damage in experimental animals: Underlying pathological mechanisms

Michael A. Trevethick, Ian Oakley, Nicholas M. Clayton, Peter Strong

Journal:

General Pharmacology: The Vascular System

Year:

1995

Language:

english

File:

PDF, 460 KB

english, 1995

27

A cell-based assay to assess the persistence of action of agonists acting at recombinant human β2 adrenoceptors

Susan Summerhill, Timothy Stroud, Roshini Nagendra, Christelle Perros-Huguet, Michael Trevethick

Journal:

Journal of Pharmacological and Toxicological Methods

Year:

2008

Language:

english

File:

PDF, 1.07 MB

english, 2008

28

Comparison of the profiles of agonists as stimulants of the β3-adrenoceptor in vitro with their gastroprotective effects in the conscious rat

A.K. Bahl, N.M. Clayton, J. Coates, D.P. Martin, I.G. Oakley, P. Strong, M.A. Trevethick

Journal:

British Journal of Pharmacology

Year:

1996

Language:

english

File:

PDF, 1.35 MB

english, 1996

29

Monoamine oxidase activities of porcine vascular endothelial and smooth muscle cells

Michael A. Trevethick, Henry J. Olverman, Jeremy D. Pearson, John L. Gordon, Geoffrey A. Lyles, Brian A. Callingham

Journal:

Biochemical Pharmacology

Year:

1981

Language:

english

File:

PDF, 856 KB

english, 1981

30

Cyclo-oxygenase inhibition does not unmask leukotriene release during ischaemia-reperfusion of the rat heart in vitro

M.A. Trevethick, A.K. Brown, G. Wright, P. Strong

Journal:

Biochemical Pharmacology

Year:

1989

Language:

english

File:

PDF, 423 KB

english, 1989

31

Inhaled muscarinic antagonists for COPD—does an anti-inflammatory mechanism really play a role?

Michael Trevethick, Nicholas Clarke, Matthew Strawbridge, Michael Yeadon

Journal:

Current Opinion in Pharmacology

Year:

2009

Language:

english

File:

PDF, 299 KB

english, 2009

32

The reassertion profiles of long acting β2-adrenoceptor agonists in the guinea pig isolated trachea and human recombinant β2-adrenoceptor

S. Patel, S. Summerhill, M. Stanley, C. Perros-Huguet, M.A. Trevethick

Journal:

Pulmonary Pharmacology & Therapeutics

Year:

2011

Language:

english

File:

PDF, 474 KB

english, 2011

33

PDE4 inhibition: a novel approach for the treatment of inflammatory bowel disease

Katharine H. Banner, Michael A. Trevethick

Journal:

Trends in Pharmacological Sciences

Year:

2004

Language:

english

File:

PDF, 210 KB

english, 2004

34

Effects of some metabolic inhibitors and sulphur-containing amino acids on sclerotium formation in Sclerotium rolfsii, S. delphinii and Sclerotinia sclerotiorum

Janet Trevethick, R.C. Cooke

Journal:

Transactions of the British Mycological Society

Year:

1971

Language:

english

File:

PDF, 197 KB

english, 1971

35

Water relations in sclerotia of some Sclerotinia and Sclerotium species

Janet Trevethick, R.C. Cooke

Journal:

Transactions of the British Mycological Society

Year:

1973

Language:

english

File:

PDF, 260 KB

english, 1973

36

Non-nutritional factors influencing sclerotium formation in some Sclerotinia and Sclerotium species

Janet Trevethick, R.C. Cooke

Journal:

Transactions of the British Mycological Society

Year:

1973

Language:

english

File:

PDF, 488 KB

english, 1973

37

Clinical audit and standard setting for symptomatic breast imaging in south thames region

P. Mills, K. Foord, P. Trevethick

Journal:

Clinical Radiology

Year:

1997

Language:

english

File:

PDF, 401 KB

english, 1997

38

The potential role of spinal cord cyclooxygenase-2 in the development of Freund's complete adjuvant-induced changes in hyperalgesia and allodynia

C.H Hay, M.A Trevethick, A Wheeldon, J.S Bowers, J.S De Belleroche

Journal:

Year:

1997

Language:

english

File:

PDF, 297 KB

english, 1997

39

Updated Audit Database for Breast Imaging/Histopathology Correlation

K Foord, R Guy, L Apthorp, K How, P Trevethick, M Ziemann

Journal:

Clinical Radiology

Year:

2001

Language:

english

File:

PDF, 776 KB

english, 2001

40

Defective metabolism of metoprolol in poor hydroxylators of debrisoquine.

MS Lennard, JH Silas, S Freestone, J Trevethick

Journal:

British Journal of Clinical Pharmacology

Year:

1982

Language:

english

File:

PDF, 423 KB

english, 1982

41

5-hydroxytryptamine-induced relaxation of neonatal porcine vena cava in vitro

Michael A. Trevethick, Wasyl Feniuk, Patrick P.A. Humphrey

Journal:

Year:

1984

Language:

english

File:

PDF, 504 KB

english, 1984

42

5-Carboxamidotryptamine: A potent agonist mediating relaxation and elevation of cyclic AMP in the isolated neonatal porcine vena cava

Michael A. Trevethick, Wasyl Feniuk, Patrick P.A. Humphrey

Journal:

Year:

1986

Language:

english

File:

PDF, 803 KB

english, 1986

43

Inhalation by Design: Novel Ultra-Long-Acting β 2 -Adrenoreceptor Agonists for Inhaled Once-Daily Treatment of Asthma and Chronic Obstructive Pulmonary Disease That Utilize a Sulfonamide Agonist Headgroup

Glossop, Paul A., Lane, Charlotte A. L., Price, David A., Bunnage, Mark E., Lewthwaite, Russell A., James, Kim, Brown, Alan D., Yeadon, Michael, Perros-Huguet, Christelle, Trevethick, Michael A., Clar

Journal:

Journal of Medicinal Chemistry

Year:

2010

Language:

english

File:

PDF, 1.13 MB

english, 2010

44

PRE-EMPLOYMENT MEDICAL EXAMINATION

Trevethick, R.A., Simpson, AlanS.

Journal:

Year:

1965

Language:

english

File:

PDF, 354 KB

english, 1965

45

MELORHEOSTOSIS

Trevethick, R.A.

Journal:

Year:

1953

Language:

english

File:

PDF, 433 KB

english, 1953

46

Transcript characterisation, gene disruption and nucleotide sequence of the Saccharomyces cerevisiaeWHI2 gene

Kelly, Diane E., Trevethick, Janet, Mountain, Harry, Sudbery, Peter E.

Journal:

Year:

1988

Language:

english

File:

PDF, 963 KB

english, 1988

47

FIRST-AID MANUALS

Trevethick, R.A.

Journal:

Year:

1956

Language:

english

File:

PDF, 190 KB

english, 1956

48

First Aid and Early Treatment of Burns in the Royal Air Force

Review by: R. A. Trevethick

Journal:

British Journal of Industrial Medicine

Year:

1958

Language:

english

File:

PDF, 244 KB

english, 1958

49

Advanced First Aid No. 1 "How Much Blood?"

Review by: R. A. Trevethick

Journal:

British Journal of Industrial Medicine

Year:

1963

Language:

english

File:

PDF, 247 KB

english, 1963

50

Occupational Health and Safety in Great Britain 1972

R. A. Trevethick

Journal:

British Journal of Industrial Medicine

Year:

1974

Language:

english

File:

PDF, 598 KB

english, 1974

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